Kamagra (sildenafil): uses, side effects, views

Sildenafil citrate, the main ingredient of Kamagra, is a phosphodiesterase type 5 (PDE5) inhibitor. Here is a rundown of how Kamagra and similar medications, such as Viagra, are used to treat erectile dysfunction (ED): Mechanism of Action: When a man is sexually aroused, nitric oxide is released in the erectile tissue of the penis. Nitric oxide causes the enzyme guanylate cyclase to become active, which increases the amount of cyclic guanosine monophosphate (cGMP). The smooth muscles in the penile blood arteries relax when there is an increase in cGMP, which allows the penis to receive greater blood flow. Enhanced Blood Flow: The result of relaxed smooth muscle and increased blood flow is an erection. This is a typical response to sexual stimulation.