Gemcitabine Hydrochloride for SARS-CoV-2

A 2'-deoxycytidine hydrochloriode with geminal fluoro substituents in the 2'-position is gemcitabine hydrochloride. This deoxycytidine analog can stop the proliferation of multiple cell lines, including BxPC-3, Mia Paca-2, PANC-1, PL-45, and AsPC-1 cells. It also prevents DNA synthesis and repair. This substance has been utilized to treat a number of carcinomas, such as non-small cell lung cancer, pancreatic cancer, bladder cancer, and breast cancer, since it inhibits ribonucleotide reductase. According to studies, gemcitabine hydrochloride can be used to treat or prevent viral illnesses.