Anti-Ad fiber knob x Anti-CEA

Ad fiber knob x CEA CrossMab is intended to be expressed as four chains with domain crossover and knobs-into-holes alterations. High-purity antibodies can be produced through one or more processes of purification. Adenoviral vectors can be retargeted by this BsAb to tumor cells. It can be applied in cancer gene therapy to deliver a therapeutic gene to tumor cells with the goal of efficient and targeted cell death.