PEGylation

With extensive experience and a team of PEGylation technical specialists, Creative Biolabs offers top-quality carbohydrate PEGylation services. We are skilled in utilizing a variety of advanced technologies to address diverse challenges. Whatever your research requirements, we are confident in developing a suitable plan for you.
 

Introduction to PEGylation
 

PEGylation offers the advantage of retaining and enhancing the desirable properties of protein therapeutics without compromising their function. The chemical, molecular, and structural properties of polyethylene glycol (PEG), along with their conformational behavior in aqueous solutions, influence the pharmacological disposition of PEGs and PEGylated products in physiological compartments. PEG molecules can vary in size and shape, providing options to modulate pharmacological outcomes for different drug therapies. PEGylating glycan structures attached to proteins allows for targeted modification at glycosylated sites, providing the benefits of PEGylation without the loss of activity that can occur with random multistep PEGylation processes.