by on August 20, 2024
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Compstatin is a 13-residue peptide that has an IC50 of 28 nM for inhibiting C3 convertase and 12 μM for inhibiting the activation of the classical and alternative complement pathways.

Compstatin has made tremendous progress in our understanding of complement inhibition.

In our investigations, we employed it to prevent complement activation and saw a noteworthy decrease in inflammatory indicators. The chemical is simple to work with and quite specific. It is a dependable tool for our lab because the outcomes were constant across several studies.
 

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