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Herpes simplex virus (HSV) belongs to the herpesvirus alpha subfamily and has a unique 4-layer structure. The core of HSV is a linear double-stranded DNA of about 152 000 bp, surrounded by an icosahedral capsid. The outer capsid is a membrane, which contains more than 20 important proteins that can regulate the virus replication cycle. It is a characteristic structure of herpes viruses, can connect the capsid and envelope to form a complete virus particle. The outermost layer of HSV is the lipid...
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