Protein is a complex organic compound composed of amino acids. Due to the hydrophilicity, hydrophobicity, positive charge, negative charge and other characteristics of amino acid residues, it can be folded into a precise 3D structure through the interaction between the residues. The sequence of amino acids determines the unique 3D structure of each protein and its specific functions. Protein participates in almost every process in the cell and is necessary to maintain the structure and function of human tissues and organs. Protein folding errors can induce a variety of degenerative diseases, such as Parkinson's disease, Alzheimer's disease, frostbite, and senile heart failure. Therefore, imaging analysis of the folding process of proteins is of great significance for the early diagnosis and treatment of diseases.
Michelle  Moser
CD BioSciences is a professional technology company providing 3D printing services and products. CD BioSciences focuses on offering a series of high-quality 3D printing materials to meet the parts production and performance requirements of different industries. The materials of CD BioSciences cover metal materials, plastic materials, ceramics and wood, and it will continue to launch new materials. At present, plastic materials are still the most commonly used materials in the 3D printing industry, which can be used in many fields such as automobiles, medical treatment, and art creation. The low cost, excellent flexibility, stability, aesthetics, durability and biocompatibility of plastic materials, and the ability to rapid prototyping, the excellent quality of these aspects make plastic materials still have an unshakable position in the field of 3D printing, although the 3D printing of other materials is rapidly developing. CD BioSciences offers a wide range of versatile plastic 3D printing materials to choose from to meet the specific needs of your application. For plastic 3D printing, various technologies have been developed, such as fused deposition modeling (FDM), selective laser sintering (SLS), stereolithography (SLA). With different plastic materials, the products made will also have different properties. In order to achieve the desired performance of your product, you need to select the most appropriate plastic material. CD BioSciences has excellent material expertise and rich 3D printing plastic materials for different applications, and can customize the corresponding plastic materials according to your needs, and strives to serve your production and creation.
Michelle  Moser
Metabolism is a term that describes the set of life-sustaining chemical reactions in organisms. It can be divided into two categories: catabolism, the breakdown of molecules, and anabolism, the synthesis of molecules. Metabolism is tightly linked to the availability of nutrients such as proteins, lipids and carbohydrates. Metabolic pathways are a series of chemical reactions of metabolism, which are catalyzed by a sequence of enzymes. However, metabolic signaling pathways refer to the cellular signaling transductions that respond to metabolic state and regulate cellular events to maintain cell and organismal homeostasis. Dysregulation of these pathways is associated width metabolic diseases such as obesity, type 2 diabetes, as well as cancer and aging.
Michelle  Moser
Mechanical properties testing is used to analyze the mechanical characteristics of materials applied with various external loads (such as tensile, compression, shear, torsion, impact, alternating stress, etc.) in different temperature, medium, and humidity. Mechanical properties testing can be applied to any stage of production, from quality control of raw materials to durability checking of finished products. STEMart provides a variety of mechanical properties testing to realize development of new materials, exploration of material potential and fault analysis of materials, help clients ensure the durability, stability and safety of materials.
Staci  Horme
Materials testing is used to understand how your materials will perform or react under a wide variety of stresses. Materials testing can also supply important information about the materials you are developing or incorporating into products to ensure they are in compliance with the expected specifications. The data collected during testing and the final test results can be very useful to engineers, designers, production managers and others. STEMart can conduct a large range of material analysis and characterization under standard guidelines and methods, and also provide custom testing according to clients' testing purposes and applications of the testing requirements.
Staci  Horme
MagIso™ DNA & RNA Magnetic Silica Particles, 600 nm are superparamagnetic silica beads with very high surface area intended for nucleic acid extraction and purification. They have low sedimentation rate and fast magnetic response (3-5 min separation time). These particles have been developed for rapid and reliable isolation of nucleic acids from whole blood, plants, tissues, bacteria and other samples.
Richard  Gray
Dengue Virus (Serotypes 1-4) Antiviral Services Dengue virus is an enveloped single-stranded positive-sense RNA virus, which belongs to the family of Flaviviridae. Dengue virus has approximately 11,000 nucleotides in length that encodes three structural (C, Env, M) and seven non-structural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5). There are four different serotypes of dengue virus (DENV 1-4) and the classification is based on structural antigens that induce type-specific antibodies at the time of infection. Dengue fever is an arthropod-borne disease caused by the dengue virus (DENV), mainly transmitted by Aedes aegypti mosquitoes. Dengue fever is the most popular mosquito-borne disease in the world. The dengue virus mainly spreads in tropical and subtropical regions, including Southeast Asia, the Americas, Africa, the Western Pacific, and the Eastern Mediterranean. Dengue virus research should be conducted using biosafety level 2 practices, equipment, and facility design. Laboratory diagnostic methods to confirm dengue virus infection may involve detection of virus, viral nucleic acid, antigen or antibody, or a combination of these techniques. The virus can be detected in serum, plasma, circulating blood cells, and other tissues for 4-5 days after onset. In the early stages of the disease, viral isolation, nucleic acid or antigen testing can be used to diagnose infection. At the end of the acute phase of infection, serology is the method of choice for diagnosis. Serological tests for dengue virus generally use IgM antibody-capture enzyme-linked immunosorbent assay (MAC-ELISA), IgG ELISA, IgM capture and IgG capture ELISAs, anti-dengue virus IgA capture ELISA, and haemagglutination-inhibition (HI) test.
Thomas  Schmitt
In the realm of medical diagnostics, the development of advanced imaging techniques has revolutionized our understanding of the human body. Among these breakthroughs is molecular imaging, a cutting-edge field that enables us to peer into the intricate mechanisms of life at a molecular level. By harnessing the power of specialized imaging technologies, scientists and healthcare professionals can explore the inner workings of cells, track disease progression, and design targeted therapies. Let us delve into the fascinating world of molecular imaging and its incredible potential to transform healthcare.
Michelle  Moser
Introduction of Wood-PLA Wood products have always been favored by people because of their unique aesthetics and practicality. Traditional wood processing methods will produce a large amount of waste such as wood chips, and it is time-consuming to manufacture complex structures. With the development of 3D printing technology, researchers began to try to apply more and more materials to 3D printing. As shown in Fig. 1, a complete large-scale podium base was 3D printed with poplar-PLA composite materials.
Michelle  Moser
Acetylation is one of the major protein modifications in cells, where the acetyl group from acetyl coenzyme A (acetyl-CoA) is transferred to a polypeptide chain. Protein acetylation can occur at N-terminal as a co-translational covalent modification by N-terminal acetyltransferases (NATs), or on lysine as a reversible post-translational modification (PTM). Like phosphorylation, acetylation also affects protein function by altering the properties of proteins such as hydrophobicity, solubility, protein conformation and affinity with other macromolecules. Thousands of acetylation have been identified in human proteome, among which chromatin proteins and metabolic enzymes are highly represented such as histones, P53, and STAT3. Consequently, dysregulation of acetylation can lead to metabolic disorders, cancers, neurodegeneration, and cardiovascular diseases. CD BioSciences offers a complete portfolio of solutions to study protein acetylation including acetylation profiling, acetyltransferase/deacetylase identification, substrate identification, and inhibitor/activator screening.
Michelle  Moser