Topic: 3d model

The development of cancer 3D models is to simulate the microenvironmental features of in vivo tumor growth along with the phenotypic and cellular heterogeneity of tumors. As in vivo tumors grow, 3D models more accurately mimic the complexity and variety of clinical malignancies than do 2D cell cultures. Numerous in vivo tumor features, including cell-cell communication, hypoxia, drug penetration, response, and resistance, as well as extracellular matrix synthesis and deposition, have been found ...