Topic: sctb

The single-chain triplebody, also known as the recombinant Anti-EGFR x Anti-CD16 Bispecific Antibody, is intended to be expressed as a single chain containing three scFv units, two distal binding sites for EGFR, and a central site for CD16. At the C/N terminus, it has a His-tag for affinity purification. NK cells can be redirected to tumor cells by this BsAb. It is intended for use in studies on solid tumor therapy, non-small cell lung cancer (NSCLC), colorectal cancer (CRC), glioblastoma multif...